Gold University of Minnesota M. Skip to main content.University of Minnesota. Home page.
Quick Links


Contact IACUC

Download Forms

Frequently Asked Questions

Policies and Guidelines


Information for:
  Public and Media

  Committee Members

OVPR Links

Office of the Vice President for Research


IACUC Office

Council of Research Associate Deans

eResearch Systems Support

Human Research Protection Program

Research Education and Oversight

Sponsored Projects Administration

Technology Commercialization

Institutional Animal Care and Use Committee
Office of the Vice President for Research



Download forms to apply for approval to use animals at the University.

Training and Certification

How to become certified to work animals at the University, training requirements.


Animal Use Policies & Guidelines

Policies, guidelines, recordkeeping forms, federal and University regulations.


eProtocol provides a common tool for principal investigators, IACUC staff and committee members to submit, review and communicate about protocols. Access is available to anyone with an x.500 user name and password.  All staff listed as working on a protocol can view the protocol details via the eProtocol system.

For more information visit:

View the short instructional video:



Grant Documents: AAALAC Accreditation Letter, NIH Assurance Information, and USDA Registration Number

1. AAALAC Accreditation Letter - For use when funding agencies request a copy of the most recent UMN AAALAC accreditation letter. Note: AAALAC accreditation applies only to facilities in the AHC, CLA, and the Hormel Institute.

2. The UMN's NIH Animal Welfare Assurance Number is A3456-01. Most recent renewal date: 4/17/12. Expiration date: 4/30/16. This applies to all UMN animal activities funded by the Public Health Service.

3. The UMN's USDA Registration Number is 41-R-0005. This applies to all UMN animal activities regulated by the USDA. Both the species of animal and the nature of the activity determines USDA regulation.




Guide for the Care and Use of Laboratory Animals (The Guide) 8th edition, 2011



NIH Vertebrate Animal Section Template

NIH scientific review groups are instructed to evaluate the five point Vertebrate Animal Section (VAS) to determine if it is complete and if plans for the use of vertebrate animals are appropriate. Points 1, 2, and 5 are relatively straightforward (describe the animals and their proposed use; provide justifications for the use of animals, choice of species, and number of animals to be used; and describe methods of euthanasia) and the level of detail required has not changed significantly. However, more detail may now be requested for Points 3 and 4 (general description of veterinary care and procedures to minimize discomfort, distress, pain and injury). A detailed worksheet on the VAS has been developed by the NIH Office of Laboratory Animal Welfare and is available at .

To assist University of Minnesota investigators who house animals in Research Animal Resources with the writing of the VAS of NIH grant proposals, a document with suggested language and advice on completing the VAS has been developed. You can view/download that document HERE.

If you have additional questions about completing the VAS, please contact the Institutional Veterinarian, Dr. Cyd Gillett, at

3/08/10, updated 1/18/13


Building Flexibility into Animal Care and Use Protocols  

In order to maintain compliance and the flexibility needed in the conduct of animal studies, it is recommended that ACUP forms be written with a range of justifiable options to use.  For example, when stating the method of euthanasia, indicate several acceptable options (eg. carbon dioxide or pentobarbital overdose). You may cut and paste standard euthanasia methods from the RAR website HERE. Do the same for anesthetic regimens (eg. ketamine/xylazine or isoflurane).  For blood collection, give a range of acceptable amounts, frequency and intervals (eg. 0.05-0.10 ul of blood will be drawn from either the tail vein or the facial vein every 1 to 3 days for no more than 14 days).  For study endpoints, give maximum times or markers (eg. animals will be euthanized no later than 3 weeks after administration of test article depending on animal condition and study progress).  For behavioral tests or radiographic examinations, give a range of timing and frequency (eg. an x-ray will be taken 2-6 times during the 10-30 days following the procedure).   The flexible options you build into an ACUP should be based in appropriate study design and reasonable choices, but careful planning at the time of ACUP completion can help minimize the need for protocol amendments in the future.  

11/05/09 rev 9/28/10




The University of Minnesota is an equal opportunity educator and employer.